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60 Resveratrol Health Benefits

Reported by Online Medical Researchers

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Resveratrol

Resveratrol and Thyroid

Resveratrol found in red wines have received near iconic praise for its versatile restorative and therapeutic health benefits that have made it among the most popular active ingredient in food supplements.

Its anti-carcinogenic action in laboratory experiments on animals promises to alter the way cancer patients can be treated. One of its main anti-cancer properties is its ability to create death signals that cause the self-destruction of tumor cells which in medical jargon is known as apoptosis.

There have been researches in its anti-cancer properties that have shown that the human thyroid

hormone L-thyroxin T4 interferes with Resveratrol’s apoptic action but the physiological mechanism have largely remained unexplained until further research into it are conducted. T4 hormones are known to promote proliferation of cancer cells.

Research Findings: Resveratrol vs Thyroid

In 2007, a research paper was published by a team from the Department of Radiation Oncology in Cleveland Ohio attempting to confirm Resveratrol and Thyroid interaction in the treatment of cultured glioma cells. It objective is to examine the mechanism whereby thyroid T4 hormones inhibit Resveratrol-induced cell apoptosis in cultured in vivo glioma cells.

The findings concluded that Resveratrol activated extra cellular kinases cPKC and EPK1/2 and result in COX-2 nuclear location in glioma cells that eventually case apoptosis. The T4 hormones introduced in Resveratrol-treated glioma cells interfered with the interaction of these two kinases that inhibited COX-2 protein formation required in apoptosis of these Resveratrol-treated glioma cells.

However, the inhibiting effect of T4 was prevented by tetraiodothyroacetic acid or tetrac which inhibited the thyroid T4 from binding to its integrin receptor without affecting Resveratrol-induced apoptosis.

The result finding may need further confirmation and duplication by other independent studies but if the results are correct, Resveratrol medication need only to be administered with Tetrac to reduce Thyroid interference on its ability to induce self destruction of cancer cells. The right dosage and concentration will have to wait for the results of human trials.

By Admin, Resveratrols.org

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