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60 Resveratrol Health Benefits

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Resveratrol and Fibroids

Uterine fibroids, also known as uterine leiomyoma and myoma, fribromyoma and fibroleiomyoma and fibroma is a benign tumor in the female uterus. While most cases are asymptomatic, they can cause painful menstruation and sexual intercourse as well as urinary incontinence.

As a benign tumor, fibroids don’t need to be treated and the lesions can be managed unless they become obstructive and painful which makes them an indication for surgical excision in the form of hysterectomy, laparoscopic myomectomy and laparatomic myomectomy, also known as open abdominal myomectomy. The malignant fibroid is rare and is known as leiomyosarcoma.

Treatment and Research: Resveratrol vs Fibroids

Reducing fibroids can be medicated and the only approved treatment is the use of gonadotropin-releasing hormone analogs of GNRH analogs which are short-term medication that lead to estrogen deficiency and eventual osteoporosis. Studies have shown the efficacy of aromatase inhibitors, progesterone antagonists and selective progesterone receptor modulators like Progenta exhibit promising treatment are under clinical investigation.

Recent studies conducted by a fibroid research team headed by Dr. Bill Catherino and published and presented at the American Society of Reproductive Medicine Conference in Atlanta indicated that Resveratrol decreases the growth and induce fibroid cell death in vitro.

The Medical School of the University of Michigan likewise studied the effects of Resveratrol-induced apoptosis on the proliferation of leiomyoma cells and concluded that a 5-day dose-dependent Resveratrol peaking at a maximum of 200 micrograms is an effective fibroid cell inhibitor using in vitro proliferation of leiomyoma cells from lab rats.

Resveratrol not only inhibited cell growth but contributed to apoptosis of leiomyoma cells. Its action had been attributed to its remarkable estrogen antagonist properties.

Further studies are needed to corroborate these findings and to confirm its efficacy using human tissues. Getting a firm grasp on the mechanism by which Resveratrol exhibits anti-tumorigenic qualities against leiomyoma cells in fibroid is essential to attaining FDA approval.

By Admin, Resveratrols.org

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