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60 Resveratrol Health Benefits

Reported by Online Medical Researchers

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Resveratrol

Resveratrol and Cancer

Since the late 90s, there have been a number of clinical studies in various labs and research facilities in universities and pharmaceutical companies across the land showing the anti-carcinogenic properties of Resveratrol, an anti-oxidant extract from red wines and grape skins.

Most of these studies are on lab animals as no results of human clinical tests on cancer cells have been reported yet, though clinical trials on colon cancer and skin cancer melanoma are having progress on human patients. Some of these tests, however, also showed conflicting and even negative results on certain types of cancer cells.

Resveratrol and Cancer Prevention

In vitro studies have shown promising effects on cells of skin, colon, prostrate, leukemia and pancreatic cancer. Resveratrol treatment appears to have initial successes in the prevention of breast or mammary tumors in animal subjects. Injected with high doses of the substance, lab mice subjects have shown decelerated growth of neuroblastomas.

In other studies, small doses of around 0.02 to 8 mg/kg of Resveratrol taken prophylactically prevented the development of colon and intestinal tumors in mice treated with various carcinogens. Moreover, when 1 mg/kg is taken orally in mice, Resveratrol reduced the incidence of esophageal cancer as well as controlled its spread.

The strongest body of evidence of its anti-cancer efficacy comes when Resveratrol had direct contact with tumor cells like in skin and gastrointestinal tract cancers.

Mixed Results

Topical application of Resveratrol before and after UVB exposure in lab mice has shown decreased incidence of skin cancer. But oral administration had not shown positive results in treating mice that have been inoculated with cancer or melanoma cells. Resveratrol also had no effect on leukemia and lung cancer when taken orally. But when 2.5 to 10 mg/kg of the substance is injected intraperitoneally, it decelerated the growth of a metastatic type of lung cancer or Lewis lung carcinoma.

Initial tests on human cancer patients have shown that even high doses may be inadequate to prevent systemic spread of cancer. More clinical studies are in the works to confirm and further explore the anti-carcinogenic properties of Resveratrol.

By Admin, Resveratrols.org

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